Neonatal Acquired Methemoglobinemia – Can Broad Spectrum Antibiotics be Implicated?
نویسندگان
چکیده
منابع مشابه
Antimicrobial peptides: broad-spectrum antibiotics from nature.
No therapeutically useful new classes of antibiotics have been identified in the past quarter of a century This has become of major consequence in the face of the increase in the incidence of significant antibiotic resistance in the past decade. Indeed, strains of several important pathogens have been identified for which very few, or even no, possibilities for antibiotic therapy exist. Althoug...
متن کاملAcquired methemoglobinemia in infants.
OBJECTIVE This study aimed to determine the etiologic factors of acquired methemoglobinemia in infants younger than three months in our region. METHODS This study was carried out retrospectively in infants with methemoglobinemia admitted to Karadeniz Technical University, Pediatric Clinic, during the period 2000-2009. Infants with methemoglobinemia were identified according to the medical rec...
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Membrane-permeabilizing peptide antibiotics are an underutilized weapon in the battle against drug-resistant microorganisms. This is true, in part, because of the bottleneck caused by the lack of explicit design principles and the paucity of simple high-throughput methods for selection. In this work, we characterize the requirements for broad-spectrum antimicrobial activity by membrane permeabi...
متن کامل5-Alkyloxytryptamines are membrane-targeting, broad-spectrum antibiotics.
Antibiotic adjuvant therapy represents an exciting opportunity to enhance the activity of clinical antibiotics by co-dosing with a secondary small molecule. Successful adjuvants decrease the concentration of antibiotics used to defeat bacteria, increase activity (in some cases introducing activity against organisms that are drug resistant), and reduce the frequency at which drug-resistant bacte...
متن کاملDrugs may be Induced Methemoglobinemia
Methemoglobinemia is a rare disorder of the blood in which there is an increase in the proportion of hemoglobin present in the oxidized form (methemoglobin). It may be inherited, due either to a deficiency of methemoglobin reductase or to a structural abnormality of hemoglobin, or it may be acquired, usually secondary to exposure to drugs or chemicals that oxidize hemoglobin Nearly 90 compounds...
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ژورنال
عنوان ژورنال: The Indian Journal of Pediatrics
سال: 2019
ISSN: 0019-5456,0973-7693
DOI: 10.1007/s12098-019-02978-5